Composition:
Each 5 ml of reconstituted susp contains cefixime trihydrate USP equivalent to cefixime 100 mg
Description:
Cinklare (Cefixime) is an antibacterial, belonging to the drug class of 3rd generation cephalosporin.
Indications:
Uncomplicated gonorrhea (cervical/urethral and rectal) caused by Neisseria gonorrhoeae, including penicillinase (beta-lactamase-positive) and nonpenicillinase (beta-lactamase-negative) producing strains..
Cinklare is indicated in the treatment of adults and pediatric patients six months of age or older with the following infections when caused by susceptible isolates of the designated bacteria:
Upper Respiratory Tract:
Pharyngitis and tonsillitis caused by S. pyogenes.
Middle Ear:
Otitis media caused by S. pneumoniae, H. influenzae (beta-lactamase positive and negative strains), M. catarrhalis (former B. catarrhalis) (beta-lactamase positive and negative strains) and S. pyogenes.
Paranasal Sinuses:
Sinusitis caused by S. pneumoniae, H. influenzae (beta-lactamase positive and negative strains), and M. catarrhalis (former B. catarrhalis) (beta-lactamase positive and negative strains).
Lower Respiratory Tract:
Acute bronchitis caused by S. pneumoniae, M. catarrhalis (former B. catarrhalis) (beta-lactamase positive and negative strains) and H. influenzae (beta-lactamase positive and negative strains).
Urinary Tract:
Acute uncomplicated cystitis and urethritis caused by E. coli, P. mirabilis, and Klebsiella species.
Uncomplicated Gonorrhea:
Uncomplicated gonorrhea (cervical/urethral and rectal) caused by Neisseria gonorrhoeae, including penicillinase (beta-lactamase-positive) and non penicillinase (beta-lactamase-negative) producing strains.
Dosage:
The recommended dose of cefixime is 8 mg/kg/day once daily. When necessary, a dose of 4 mg/kg given twice daily may be considered except for urinary tract infections where once-daily dosing must be used.