Composition:
EachGluconorm tablet contains glimepiride 2 mg asactive ingredient.
Description:
Gluconorm(glimepiride) is an oral blood-glucose-lowering drug of the sulfonylurea class.
Indications:
Gluconormis indicated:
Asan adjunct to diet and exercise to lower the blood glucose in patients with noninsulin-dependent (Type 2) diabetes mellitus (NIDDM) whose hyperglycemia cannot be controlled by diet and exercise alone.
Concomitantly with metformin when diet, exercise and Gluconorm or metformin alone do not result in adequate glycemic control.
In combination with insulin to lower blood glucose in patients whose hyperglycemia cannot be controlled by diet and exercise in conjunction with an oral hypoglycemic agent. Combined use of glimepiride and insulin may increase the potential for hypoglycemia.
Dosage:
Usual Starting Dose:
The usual starting dose of Gluconorm as initial therapy is 1-2 mg once daily, administered with breakfast or the first main meal.
The maximum starting dose of Gluconorm should be no more than 2 mg.
Usual Maintenance Dose:
The usual maintenance dose is 1 to 4 mg once daily.
The maximum recommended dose is 8 mg once daily.
Gluconorm-Metformin Combination Therapy:
If patients do not respond adequately to the maximal dose of Gluconorm monotherapy, addition of metformin may be considered.
With concomitant Gluconorm and metformin therapy, the desired control of blood glucose may be obtained by adjusting the dose of each drug.
Gluconorm-Insulin Combination Therapy:
Combination therapy with Gluconorm and insulin may also be used in secondary failure patients. The recommended Gluconorm dose is 8 mg once daily administered with the first main meal.
After starting with low-dose insulin, upward adjustments of insulin can be done approximately weekly as guided by frequent measurements of fasting blood glucose.