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TYPHIM VACCINE
₨ 3,216
Description
The TYPHIM Vi vaccine (manufactured by Sanofi Pasteur) is an injectable, single-dose vaccine for the prevention of typhoid fever in individuals aged 2 years and older. It is a Vi capsular polysaccharide (ViPS) vaccine, a type of unconjugated vaccine.
Key Facts
- Indication: Active immunization against typhoid fever caused by the bacterium Salmonella typhi. It does not protect against Salmonella paratyphi or other enteric bacteria.
- Administration: A single 0.5 mL dose is administered via intramuscular injection.
- Target Population: Approved for use in adults and children at least 2 years old.
- Efficacy: Estimated to be about 50% to 85% effective, providing protection for a limited duration. In clinical trials, a single dose offered about 55% protection over a 3-year period in an endemic area study.
- Booster Doses: Reimmunization (a booster dose) is recommended every 2 to 3 years for individuals who remain at risk of exposure.
- Mechanism: The vaccine is made from the purified Vi capsular polysaccharide from the Salmonella typhi bacterium.
Who is it Recommended For?
The vaccine is not typically recommended for routine immunization in the United States but is recommended for selective immunization in specific circumstances:
- Travelers: Individuals traveling to areas where typhoid fever is common (e.g., Africa, Asia, Central/South America), particularly those with prolonged exposure to potentially contaminated food and water. The vaccine should be administered at least two weeks before expected exposure.
- Close Contacts: Persons with intimate, continued household contact with a documented typhoid carrier.
- Laboratory Workers: Individuals who work frequently with Salmonella typhi in a microbiology laboratory setting.
Common Side Effects
Most adverse reactions are minor and transient, primarily local reactions at the injection site.
- Very Common: Pain, tenderness, redness (erythema), and swelling/induration (a hard lump) at the injection site.
- Common Systemic Effects: Headache, malaise (general discomfort), fatigue, and low-grade fever.
Important Considerations
- Food and Water Safety: Even after vaccination, it is crucial to practice caution in selecting food and water sources as no vaccine is 100% effective and the vaccine does not protect against other food/water-borne illnesses.
- Contraindications: The vaccine should not be administered to anyone with a history of a severe allergic reaction (hypersensitivity) to any of its components.
- Pregnancy/Breastfeeding: Use during pregnancy is only recommended if clearly needed and the potential benefits outweigh the risks.
- Storage: The vaccine must be stored in a refrigerator between +2°C and +8°C (35°F and 46°F) and protected from light.
DISCLAIMER
Super Health’s intention is to make sure that its consumers get information that is accurate, reviewed by an expert, and error-free. However, the information mentioned here should not be used as a replacement for the advice of a qualified physician. The information given here is for informational purposes only, and may not cover all possible precautions, side effects, contraindications, or drug interactions. Consult your doctor and discuss your queries related to any medicine or disease.
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