Rivaclot Tab is an anticoagulant medication whose blood-thinning ability makes it an effective agent to minimize the risk of life-threatening cardiovascular diseases which occur due to the formation of blood clots. It works by inhibiting the factor Xa involved in the coagulation cascade, thereby reducing the likeliness of developing blood clots. Due to its anticoagulant properties, Rivaclot Tablet  is used for the treatment and prevention of Deep Vein thrombosis (DVT), Pulmonary Embolism (PE), atrial fibrillation, unstable angina, coronary and peripheral artery diseases, and stroke.

Rivaclot Tablet is the first oral anticoagulant that directly causes the inhibition of factor Xa and hence ensures streamlined blood through the veins. Routine monitoring of INR (International normalized is not necessary as done in the case of other anticoagulants (Warfarin). Rivaclot Tabletis a prescription-only medicine and can only be administered upon the suggestion of a healthcare practitioner.

Premature discontinuation of Rivaclot  Tablet  should be avoided as it may put you at increased risk of thrombotic events such as spinal or epidural hematoma (blood accumulates in the epidural space, compressing the spinal cord). Rivaclot  Tablet in low doses e.g. 10mg can be taken with or without food but the dose 15mg and 20mg of the tablet should be taken along with food for better absorption.

Indications

Rivaclot Tablet  is prescribed in the following clinical conditions:

• Prevention of thrombosis in people who have undergone hip or knee replacement surgery.
• Chronic coronary artery disease
• Chronic peripheral artery disease
• Prevention of atherothrombosis in patients with raised cardiac biomarkers (along with other antiplatelets such as Acetyl Salicylic acid, ticlopidine, and Clopidogrel)
• Prevention of stroke in people with atrial fibrillation (irregular heartbeat that can create a clot that may travel to the brain and cause stroke)
• Treatment of recurrent Deep Vein Thrombosis (blood clot in the veins of legs) and Pulmonary embolism (Blood clot in the lung)
• Reduction of vascular thrombosis
• Reduction of the risk of major cardiovascular diseases
• A low dose of acetylsalicylic acid reduces the risk of life-threatening heart diseases such as stroke, heart attack, and coronary artery disease.
• In children (not younger than 2 years of age) for the treatment of congenital heart disease after the Fontan procedure (a type of open-heart surgery).
• For the prevention and treatment of VTE (Venous thromboembolism) in pediatrics and adolescents.

How Does Rivaclot  Tablet Work

Rivaclot  Tablet is a selective inhibitor of factor Xa which is involved in the intrinsic and extrinsic pathway of blood coagulation. Factor Xa is a blood clotting factor that is required for the activation of prothrombin (factor II) to thrombin (factor IIa) and also for the activation of fibrinogen into fibrin (a loose meshwork that makes up the clot). Clot formation cannot occur without the presence of these two major factors (thrombin and fibrin). So, by the inhibition of a catalyst of blood coagulation cascade i.e. factor Xa, Rivaclot  Tablet ceases the progression of clot formation and hence produces its anti-platelet effect.